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In Vivo Ready™ Anti-Human CD178 (Fas ligand) (NOK-1)

Sizes available: 100 µg

Applications: FC, FA
SKU: 40-9919
In Vivo Ready™ Anti-Human CD178 (Fas ligand) (NOK-1) is available for purchase in increments of 1
Product Name Price Qty
In Vivo Ready™ Anti-Human CD178 (Fas ligand) (NOK-1) ..... Cat.No. 40-9919-U100 ..... Size 100 µg
$104.00

Description

Details

The NOK-1 antibody reacts with human CD178 (Fas ligand) in both membrane bound and soluble forms. Fas ligand is a 40 kDa transmembrane glycoprotein, a member of the TNF family, and is expressed by activated T and NK cells, neutrophils, and monocytes. Interactions between CD178 (Fas ligand) and CD95 (Fas) induce a program of apoptosis and play a key role in immune regulation and homeostasis. The extracellular domain of human CD178 can be cleaved from the surface by matrix metalloproteinases (MMPs) resulting in a 26 kDa soluble protein.

Additional Info

Additional Info

Name In Vivo Ready™ Anti-Human CD178 (Fas ligand) (NOK-1)
Cat. No. 40-9919
Technical Data Sheet Download TDS
Alternative Names CD95L, Fas ligand, FasL
Gene ID 356
Clone NOK-1
Isotype Mouse IgG1, kappa
Reactivity No
Cross Reactivity No
Format In Vivo Ready™
Application Flow Cytometry, Functional Assays
Citations*

Tanaka M, Suda T, Takahashi T, and Nagata S. 1995. EMBO J. 14(6):1129-1135.

Kayagaki N, Kawasaki A, Ebata T, Ohmoto H, Ikeda S, Inoue S, Yoshino K, Okumura K, and Yagita H. 1995. J Exp Med. 182(6):1777-1783.

Suda T, Hashimoto H, Tanaka M, Ochi T, Nagata S. 1997. J Exp Med. 186(12):2045-2050.

Ehrenschwender M, Wajant H. 2009. Adv Exp Med Biol. 647:64-93.

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Application Key:
FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHCF = Immunohistochemistry, Frozen Tissue; IHCP = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy


*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.