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Recombinant Human BMP-6 (Carrier-free)

Sizes available: 2 µg, 10 µg, 100 µg, 500 µg
Applications: Bioassay
SKU: 21-7004
Recombinant Human BMP-6 (Carrier-free) is available for purchase in increments of 1
Product Name Price Qty
Recombinant Human BMP-6 (Carrier-free) ..... Cat.No. 21-7004-U002 ..... Size 2 µg
$76.00
Recombinant Human BMP-6 (Carrier-free) ..... Cat.No. 21-7004-U010 ..... Size 10 µg
$175.00
Recombinant Human BMP-6 (Carrier-free) ….. Cat.No. 21-7004-U100 ….. Size 100 µg
$1,025.00
Recombinant Human BMP-6 (Carrier-free) ..... Cat.No. 21-7004-U500 ..... Size 500 µg
$3,100.00

Description

Details

Bone Morphogenetic Proteins (BMPs) belong to the TGF-beta superfamily of proteins. BMPs elicit their effects by signaling through serine/threonine kinase receptors and play key roles in the development of nearly all organs and tissues by inducing the growth of bone and cartilage. Additionally, BMP-6 plays a key role in regulating hepcidin, a liver peptide that regulates iron metabolism in mammals.

Additional Info

Additional Info

Name Recombinant Human BMP-6 (Carrier-free)
Cat. No. 21-7004
Technical Data Sheet Download TDS
Alternative Names VGR, Bone Morphogenic Protein 6
Amino Acid Sequence VSSASDYNSS ELKTACRKHE LYVSFQDLGW QDWIIAPKGY AANYCDGECS FPLNAHMNAT NHAIVQTLVH LMNPEYVPKP CCAPTKLNAI SVLYFDDNSN VILKKYRNMV VRACGCH
Authenticity Verified by N-terminal and Mass Spectrometry analyses (when applicable).
Bioactivity Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells. The expected ED50 this effect is 0.03-0.06 µg/ml.
Endotoxin Level Endotoxin level is <0.1 ng/μg of protein (<1 EU/μg).
Molecular Mass Recombinant human BMP-6 is a 26.2 kDa homodimeric glycoprotein consisting of two 117 amino acid subunits, which correspond to amino acid residues 397 to 513 of the full-length BMP-6 precursor.
Protein Content Content Verified by UV Spectroscopy and/or SDS-PAGE gel.
Purity (%) 95
Source HEK293 cells
Reactivity Human
Research Areas Angiogenesis/Cardiovascular; Apoptosis; Bone, Skeletal, Cartilage; Proliferation; Stem Cells & Differentiation; TGF-beta Superfamily
Reconstitution See Certificate of Analysis (COA) for lot specific reconstitution information.
Applications Bioassay
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Applications Guide:
FC = Flow Cytometry, FA = Functional Assays, ICC = Immunocytochemistry, IHC = Immunohistochemistry, IHCF = Immunohistochemistry, Frozen Tissue, IHCP = Immunohistochemistry, Paraffin-embedded Tissue, IF = Immunofluorescence Microscopy, IP = Immunoprecipitation, WB = Western Blot, EM = electron microscopy


*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.