Toll-Free Customer Service (855) 848-6626 | 6:00 a.m.-5:00 p.m. PT

Free Shipping on Orders Over $500 View Details

Your valued source for Immunology Tools

Recombinant Mouse Granzyme B (Carrier-Free)

Sizes available: 2 µg, 10 µg, 100 µg, 500 µg
Applications: Bioassay
SKU: 21-9094
Recombinant Mouse Granzyme B (Carrier-Free) is available for purchase in increments of 1
Product Name Price Qty
Recombinant Mouse Granzyme B (Carrier-Free) ..... Cat.No. 21-9094-U002 ..... Size 2 µg
$80.00
Recombinant Mouse Granzyme B (Carrier-Free) ..... Cat.No. 21-9094-U010 ..... Size 10 µg
$195.00
Recombinant Mouse Granzyme B (Carrier-Free) ..... Cat.No. 21-9094-U100 ..... Size 100 µg
$1,560.00
Recombinant Mouse Granzyme B (Carrier-Free) ..... Cat.No. 21-9094-U500 ..... Size 500 µg
$4,680.00

Description

Details

Granzyme B is a cysteine protease found in the cytoplasmic granules of cytolytic T lymphocytes (CTL) and natural killer (NK) cells. Granzyme B is required for the induction of target cell lysis, which occurs as part of cell-mediated immune responses, and can activate apoptosis in target cells by both caspase-dependent and caspase-independent mechanisms. Recombinant Mouse Granzyme B is a glycosylated 227 amino acid protein, comprising the mature active portion of the Mouse Granzyme B precursor.

Additional Info

Additional Info

Name Recombinant Mouse Granzyme B (Carrier-Free)
Cat. No. 21-9094
Technical Data Sheet Download TDS
Alternative Names Cytotoxic cell protease 1 (CCP1)
Amino Acid Sequence IIGGHEVKPH SRPYMALLSI KDQQPEAICG GFLIREDFVL TAAHCEGSII NVTLGAHNIK EQEKTQQVIP MVKCIPHPDY NPKTFSNDIM LLKLKSKAKR TRAVRPLNLP RRNVNVKPGD VCYVAGWGRM APMGKYSNTL QEVELTVQKD RECESYFKNR YNKTNQICAG DPKTKRASFR GDSGGPLVCK KVAAGIVSYG YKDGSPPRAF TKVSSFLSWI KKTMKSS
Authenticity Verified by N-terminal and Mass Spectrometry analyses (when applicable).
Bioactivity Determined by its ability to cleave a synthetic chromogentic Granzyme B substrate. The expected specific activity, when using the Ac-IEPD-pNA substrate at 25οC, is greater than 750 nM/min per ug of enzyme.
Endotoxin Level Endotoxin level is <0.1 ng/μg of protein (<1EU/μg).
Molecular Mass The apparent molecular weight is 28.9 kDa by mass spectrometry.
Protein Content Content Verified by UV Spectroscopy and/or SDS-PAGE gel.
Purity (%) 98
Source Baculovirus
Reactivity Mouse
Research Areas Immune System, Transplantation, Inflammation, Apoptosis
Reconstitution See Certificate of Analysis (COA) for lot specific reconstitution information.
Application Bioassay
Need Another Format? Inquire Here

Application Key:
FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHCF = Immunohistochemistry, Frozen Tissue; IHCP = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy


*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.