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Recombinant Human MMP-1 (Carrier-Free)

Sizes available: 2 µg, 10 µg, 50 µg, 100 µg
Applications: Bioassay
SKU: 21-9196
Recombinant Human MMP-1 (Carrier-Free) is available for purchase in increments of 1
Product Name Price Qty
Recombinant Human MMP-1 (Carrier-Free) ..... Cat.No. 21-9196-U002 ..... Size 2 µg
$80.00
Recombinant Human MMP-1 (Carrier-Free) ..... Cat.No. 21-9196-U010 ..... Size 10 µg
$195.00
Recombinant Human MMP-1 (Carrier-Free) ..... Cat.No. 21-9196-U050 ..... Size 50 µg
$624.00
Recombinant Human MMP-1 (Carrier-Free) ..... Cat.No. 21-9196-U100 ..... Size 100 µg
$1,040.00

Description

Details

Matrix metalloproteinases (MMPs) are a family of endoproteases that require zinc and calcium for expressing catalytic activity. These enzymes play a central role in the maintenance and remodeling of the extracellular matrix.

Additional Info

Additional Info

Name Recombinant Human MMP-1 (Carrier-Free)
Cat. No. 21-9196
Technical Data Sheet Download TDS
Alternative Names Matrix Metalloproteinase-1, Fibroblast Collagenase, Interstitial Collagenase
Amino Acid Sequence MFVLTEGNPR WEQTHLTYRI ENYTPDLPRA DVDHAIEKAF QLWSNVTPLT FTKVSEGQAD IMISFVRGDH RDNSPFDGPG GNLAHAFQPG PGIGGDAHFD EDERWTNNFR EYNLHRVAAH ELGHSLGLSH STDIGALMYP SYTFSGDVQL AQDDIDGIQA IYGRSQNPVQ PIGPQTPKAC DSKLTFDAIT TIRGEVMFFK DRFYMRTNPF YPEVELNFIS VFWPQLPNGL EA
Authenticity Verified by N-terminal and Mass Spectrometry analyses (when applicable).
Bioactivity MMP-1 activity was measured by its ability to cleave a chromogenic peptide MMP-1 substrate at room temperature. At an MMP-1 concentration of 2.5 ug/ml, 50% cleavage was achieved at an incubation time of approximately 25 minutes.
Endotoxin Level Endotoxin level is <0.1 ng/μg of protein (<1EU/μg).
Molecular Mass Recombinant Human MMP-1 is a 42.7 kDa protein containing the entire catalytic N-terminal domain and the C-terminal domain, which is involved in substrate specificity, and in binding TIMP-1.
Protein Content Content Verified by UV Spectroscopy and/or SDS-PAGE gel.
Purity (%) 90
Source HEK293 cells
Reactivity Human
Research Areas Inflammation, Wound Healing, Angiogenesis/Cardiovascular, Bone Skeletal, Cartilage, Cancer
Reconstitution See Certificate of Analysis (COA) for lot specific reconstitution information.
Application Bioassay
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Application Key:
FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHCF = Immunohistochemistry, Frozen Tissue; IHCP = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy


*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.