Toll-Free Customer Service (855) 848-6626 | 6:00 a.m.-5:00 p.m. PT

Free Shipping on Orders Over $500 View Details

Your valued source for Immunology Tools

Recombinant Human MMP-2 (Carrier-free)

Sizes available: 2 µg, 10 µg, 100 µg, 500 µg
Applications: Bioassay
SKU: 21-7072
Recombinant Human MMP-2 (Carrier-free) is available for purchase in increments of 1
Product Name Price Qty
Recombinant Human MMP-2 (Carrier-free) ..... Cat.No. 21-7072-U002 ..... Size 2 µg
$69.00
Recombinant Human MMP-2 (Carrier-free) ..... Cat.No. 21-7072-U010 ..... Size 10 µg
$179.00
Recombinant Human MMP-2 (Carrier-free) ….. Cat.No. 21-7072-U100 ….. Size 100 µg
$955.00
Recombinant Human MMP-2 (Carrier-free) ..... Cat.No. 21-7072-U500 ..... Size 500 µg
$2,860.00

Description

Details

Matrix Metalloproteinase-2 (MMP-2) belongs to the matrix metalloproteinase family of endoproteases that function in the breakdown of extracellular matrix (ECM) in various normal and disease processes. MMP-2 targets type IV collagen, as well as type V, VII and X collagens, aggrecan, link protein, elastin and fibronectin. MMP­2 has been shown to be associated with many connective tissue cells as well as neutrophils, macrophages and monocytes. MMP expression and activity are tightly regulated, both through the need to activate the inactive zymogen, and control through tissue inhibitors of matrix metalloproteinases (TIMPs).

Additional Info

Additional Info

Name Recombinant Human MMP-2 (Carrier-free)
Cat. No. 21-7072
Technical Data Sheet Download TDS
Alternative Names Matrix metalloproteinase-2; Gelatinase A, TBE-1
Amino Acid Sequence MYNFFPRKPK WDKNQITYRI IGYTPDLDPE TVDDAFARAF QVWSDVTPLR FSRIHDGEAD IMINFGRWEH GDGYPFDGKD GLLAHAFAPGT GVGGDSHFDDD ELWTLGEGQV VRVKYGNADGE YCKFPFLFNGK EYNSCTDTGRS DGFLWCSTTYNF EKDGKYGFCPHE ALFTMGGNAEG QPCKFPFRFQ GTSYDSCTTE GRTDGYRWCG TTEDYDRDKKY GFCPETAMST VG
Authenticity Verified by N-terminal and Mass Spectrometry analyses (when applicable).
Bioactivity MMP-2 activity was measured by its ability to cleave a chromogenic peptide MMP-2 substrate at room temperature. At an MMP-2 concentration of 2.5 µg/ml, 50% cleavage was achieved at an incubation time of approximately 25 minutes.
Endotoxin Level Endotoxin level is <0.1 ng/μg of protein (<1 EU/μg).
Molecular Mass Recombinant human MMP-2 is a 62.0 kDa protein containing the entire catalytic N-terminal domain and the C-terminal domain (552 amino acids).
Protein Content Content Verified by UV Spectroscopy and/or SDS-PAGE gel.
Purity (%) 90
Source E. coli
Reactivity Human
Research Areas Angiogenesis/Cardiovascular; Bone, Skeletal, Cartilage; Cancer; Wound Healing
Reconstitution See Certificate of Analysis (COA) for lot specific reconstitution information.
Application Bioassay
Need Another Format? Inquire Here

Application Key:
FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHCF = Immunohistochemistry, Frozen Tissue; IHCP = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy


*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.