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Recombinant Human NT-4 (Carrier-free)

Sizes available: 2 µg, 10 µg, 100 µg, 500 µg
Applications: Bioassay
SKU: 21-7078
Recombinant Human NT-4 (Carrier-free) is available for purchase in increments of 1
Product Name Price Qty
Recombinant Human NT-4 (Carrier-free) ..... Cat.No. 21-7078-U002 ..... Size 2 µg
$76.00
Recombinant Human NT-4 (Carrier-free) ..... Cat.No. 21-7078-U010 ..... Size 10 µg
$175.00
Recombinant Human NT-4 (Carrier-free) ….. Cat.No. 21-7078-U100 ….. Size 100 µg
$1,025.00
Recombinant Human NT-4 (Carrier-free) ..... Cat.No. 21-7078-U500 ..... Size 500 µg
$3,100.00

Description

Details

NT-4 (Neurotrophin-4) is a member of the NGF family of neurotrophins that is comprised of at least four proteins including NGF, BDNF, NT-3, and NT-4/5. Neurotrophins are critical to the development of the central and peripheral nervous system and they play important roles in injury induced neuron regeneration. NT-3 is expressed in the prostate, thymus, placenta and skeletal muscle and promotes the survival of peripheral sensory sympathetic neurons. NT-4 is a secreted protein that primarily signals through the LNGFR and trkB receptors.

Additional Info

Additional Info

Name Recombinant Human NT-4 (Carrier-free)
Cat. No. 21-7078
Technical Data Sheet Download TDS
Alternative Names Neurotrophin-4, Neurotrophic 4/5 (NT-4/NT-5)
Amino Acid Sequence GVSETAPASR RGELAVCDAV SGWVTDRRTA VDLRGREVEV LGEVPAAGGS PLRQYFFETR CKADNAEEGG PGAGGGGCRG VDRRHWVSEC KAKQSYVRAL TADAQGRVGW RWIRIDTACV CTLLSRTGRA
Authenticity Verified by N-terminal and Mass Spectrometry analyses (when applicable).
Bioactivity Determined by the dose-dependent induction of choline acetyl transferase activity in rat basal forebrain primary septal cell cultures was found to be in the range of 20-50 ng/ml.
Endotoxin Level Endotoxin level is <0.1 ng/μg of protein (<1 EU/μg).
Molecular Mass Recombinant human NT-4 is a noncovalently linked homodimer, of two 14.0 kDa polypeptide monomers (260 total amino acid residues).
Protein Content Content Verified by UV Spectroscopy and/or SDS-PAGE gel.
Purity (%) 98
Source E. coli
Reactivity Human
Research Areas Diabetes / Weight Regulation; Neurobiology; Stem Cells & Differentiation
Reconstitution See Certificate of Analysis (COA) for lot specific reconstitution information.
Applications Bioassay
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Applications Guide:
FC = Flow Cytometry, FA = Functional Assays, ICC = Immunocytochemistry, IHC = Immunohistochemistry, IHCF = Immunohistochemistry, Frozen Tissue, IHCP = Immunohistochemistry, Paraffin-embedded Tissue, IF = Immunofluorescence Microscopy, IP = Immunoprecipitation, WB = Western Blot, EM = electron microscopy


*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.