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Recombinant Human Midkine (Carrier-free)

Sizes available: 5 µg, 20 µg, 100 µg, 500 µg
Applications: Bioassay
SKU: 21-7112
Recombinant Human Midkine (Carrier-free) is available for purchase in increments of 1
Product Name Price Qty
Recombinant Human Midkine (Carrier-free) ..... Cat.No. 21-7112-U005 ..... Size 5 µg
$76.00
Recombinant Human Midkine (Carrier-free) ..... Cat.No. 21-7112-U020 ..... Size 20 µg
$175.00
Recombinant Human Midkine (Carrier-free) ..... Cat.No. 21-7112-U100 ..... Size 100 µg
$585.00
Recombinant Human Midkine (Carrier-free) ..... Cat.No. 21-7112-U500 ..... Size 500 µg
$1,795.00

Description

Details

Midkine, also known as neurite growth-promoting factor 2, is a heparin-binding nonglycosylated low molecular weight protein. It is expressed in a variety of cell types during embryogenesis, and has functions related to cell growth, migration and angiogenesis. Midkine signals through the anaplastic lymphoma kinase (ALK) receptor which stimulates phosphorylation and kinase activation events and results in cell proliferation.

Additional Info

Additional Info

Name Recombinant Human Midkine (Carrier-free)
Cat. No. 21-7112
Technical Data Sheet Download TDS
Alternative Names MK, NEGF-2, neurite growth-promoting factor 2, ARAP, amphiregulin-associated protein, MDK, MEK, MK1, midgestation and kidney protein, MKARAP
Amino Acid Sequence VAKKKDKVKK GGPGSECAEW AWGPCTPSSK DCGVGFREGT CGAQTQRIRC RVPCNWKKEF GADCKYKFEN WGACDGGTGT KVRQGTLKKA RYNAQCQETI RVTKPCTPKT KAKAKAKKGK GKD
Authenticity Verified by N-terminal and Mass Spectrometry analyses (when applicable).
Bioactivity Within a concentration range of 0.1-10.0 ng/ml, the ability to chemoattract human neutrophils is measured.
Endotoxin Level Endotoxin level is <0.1 ng/μg of protein (<1 EU/μg).
Molecular Mass Recombinant Human Midkine consists of 123 amino acid residues including five intra-molecular disulfide bonds, and has a molecular weight of 13.4 kDa.
Protein Content Verified by UV Spectroscopy and/or SDS-PAGE gel.
Purity (%) 98
Source E. coli
Reactivity Human
Research Areas Angiogenesis & Cardiovascular, Neurobiology
Reconstitution See Certificate of Analysis (COA) for lot specific reconstitution information.
Application Bioassay
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Application Key:
FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHCF = Immunohistochemistry, Frozen Tissue; IHCP = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy


*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.