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Recombinant Human BDNF (Carrier-free)

Sizes available: 2 µg, 10 µg, 100 µg, 500 µg
Applications: Bioassay
SKU: 21-8366
Recombinant Human BDNF (Carrier-free) is available for purchase in increments of 1
Product Name Price Qty
Recombinant Human BDNF (Carrier-free) ..... Cat.No. 21-8366-U002 ..... Size 2 µg
$76.00
Recombinant Human BDNF (Carrier-free) ..... Cat.No. 21-8366-U010 ..... Size 10 µg
$175.00
Recombinant Human BDNF (Carrier-free) ….. Cat.No. 21-8366-U100 ….. Size 100 µg
$990.00
Recombinant Human BDNF (Carrier-free) ..... Cat.No. 21-8366-U500 ..... Size 500 µg
$2,945.00

Description

Details

Brain-derived neurotrophic factor (BDNF) is a member of the neurotrophic growth factor family of proteins that are critical for the differentiation and survival of several classes of neurons in both the central nervous system and the peripheral nervous system. BDNF binds to and mediates its neurotrophic properties through the tyrosine kinase receptor TrkB. BDNF is synthesized and secreted as a prepropeptide that is proteolytically processed to yield the mature protein. Mouse and Human BDNF sequences are identical.

Additional Info

Additional Info

Name Recombinant Human BDNF (Carrier-free)
Cat. No. 21-8366
Technical Data Sheet Download TDS
Alternative Names Brain Derived Neurotrophic Factor
Amino Acid Sequence MHSDPARRGE LSVCDSISEW VTAADKKTAV DMSGGTVTVL EKVPVSKGQL KQYFYETKCN PMGYTKEGCR GIDKRHWNSQ CRTTQSYVRA LTMDSKKRIG WRFIRIDTSC VCTLTIKRGR
Authenticity Verified by N-terminal and Mass Spectrometry analyses (when applicable).
Bioactivity Determined by its ability to stimulate the proliferation of rat C6 cells. The expected ED50 for this effect is 0.5-1.0 µg/ml.
Endotoxin Level Endotoxin level is <0.1 ng/μg of protein (<1 EU/μg).
Molecular Mass Recombinant human BDNF is a 27.0 kDa homodimer of two 120 amino acid subunits linked by strong non-covalent interactions.
Protein Content Content Verified by UV Spectroscopy and/or SDS-PAGE gel.
Purity (%) 98
Source E. coli
Reactivity Human
Research Areas Neurobiology; Proliferation; Stem Cells & Differentiation
Reconstitution See Certificate of Analysis (COA) for lot specific reconstitution information.
Application Bioassay
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Application Key:
FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHCF = Immunohistochemistry, Frozen Tissue; IHCP = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy


*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.