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Description
Details
EG-VEGF, also known as prokineticin-1, is a member of the AVIT (prokineticin) family known to strongly contract gastrointestinal (GI) smooth muscle. EG-VEGF is a secreted angiogenetic mitogen growth factor that induces proliferation, migration, and fenestration in capillary endothelial cells derived from endocrine glands. The steroidogenic glands (ovary, testis, adrenal gland, and placenta) express EG-VEGF and expression is known to be induced by hypoxia. EG-VEGF and VEGF may function in a coordinated manner as their expression is often complementary. The murine EG-VEGF gene codes for a 105 amino acid polypeptide containing an N-terminal signal sequence of 19 amino acids.
Additional Info
Additional Info
| Name | Recombinant Mouse EG-VEGF (Carrier-free) |
|---|---|
| Cat. No. | 21-7180 |
| Technical Data Sheet | Download TDS |
| Alternative Names | Endocrine Gland-derived Vascular Endothelial Growth Factor, Prokineticin 1, PROK1 |
| Amino Acid Sequence | AVITGACERD IQCGAGTCCA ISLWLRGLRL CTPLGREGEE CHPGSHKIPF LRKRQHHTCP CSPSLLCSRF PDGRYRCFRD LKNANF |
| Authenticity | Verified by N-terminal and Mass Spectrometry analyses (when applicable). |
| Bioactivity | Data Not Available. |
| Endotoxin Level | Endotoxin level is <0.1 ng/μg of protein (<1EU/μg). |
| Molecular Mass | Recombinant Mouse EG-VEGF is a 9.6 kDa protein consisting of 86 amino acid residues, including ten cysteine residues that potentially form five pairs of intra-molecular disulfide bonds. |
| Protein Content | Content Verified by UV Spectroscopy and/or SDS-PAGE gel. |
| Purity (%) | 98 |
| Source | E.coli |
| Reactivity | Mouse |
| Research Areas | Angiogenesis & Cardiovascular, Proliferation |
| Reconstitution | See Certificate of Analysis (COA) for lot specific reconstitution information. |
| Application | Bioassay |