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Recombinant Human sDLL-4 (Carrier-free)

Sizes available: 5 µg, 25 µg, 100 µg, 500 µg
Applications: Bioassay
SKU: 21-7177
Recombinant Human sDLL-4 (Carrier-free) is available for purchase in increments of 1
Product Name Price Qty
Recombinant Human sDLL-4 (Carrier-free) ..... Cat.No. 21-7177-U005 ..... Size 5 µg
$76.00
Recombinant Human sDLL-4 (Carrier-free) ..... Cat.No. 21-7177-U025 ..... Size 25 µg
$175.00
Recombinant Human sDLL-4 (Carrier-free) ..... Cat.No. 21-7177-U100 ..... Size 100 µg
$585.00
Recombinant Human sDLL-4 (Carrier-free) ..... Cat.No. 21-7177-U500 ..... Size 500 µg
$1,750.00

Description

Details

Delta-like protein 4 (DLL-4) is a type I transmembrane protein that belongs to the Delta/Serrate/Lag-2 (DSL) family of Notch ligands. DLL-4 activates through the Notch-1 and Notch-4 signaling pathways required in vascular development and homeostasis. In mice targeted deletion of the DLL-4 gene results in severe vascular defects and is lethal.

Additional Info

Additional Info

Name Recombinant Human sDLL-4 (Carrier-free)
Cat. No. 21-7177
Technical Data Sheet Download TDS
Alternative Names soluble DLL-4, Delta-like protein 4, Drosophila Delta homolog 4
Amino Acid Sequence SGVFQLQLQE FINERGVLAS GRPCEPGCRT FFRVCLKHFQ AVVSPGPCTF GTVSTPVLGT NSFAVRDDSS GGGRNPLQLP FNFTWPGTFS LIIEAWHAPG DDLRPEALPP DALISKIAIQ GSLAVGQNWL LDEQTSTLTR LRYSYRVICS DNYYGDNCSR LCKKRNDHFG HYVCQPDGNL SCLPGWTGEY CQQPICLSGC HEQNGYCSKP AECLCRPGWQ GRLCNECIPH NG
Authenticity Verified by N-terminal and Mass Spectrometry analyses (when applicable).
Bioactivity The sDLL-4, when immobilized at concentrations >1.5 μg/mL, will inhibit myogenesis in C2C12 cells.
Endotoxin Level Endotoxin level is <0.1 ng/μg of protein (<1EU/μg).
Molecular Mass Recombinant Human sDLL-4 is the 54.3 kDa, 498 amino acid glycoprotein comprised of the extracellular signaling domain of the DLL-4 protein.
Protein Content Content Verified by UV Spectroscopy and/or SDS-PAGE gel.
Purity (%) 95
Source HEK293 cells
Reactivity Human
Research Areas Angiogensis & Cardiovascular, Apoptosis, Cancer, Proliferation, Stem Cells & Differentiation
Reconstitution See Certificate of Analysis (COA) for lot specific reconstitution information.
Applications Bioassay
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Applications Guide:
FC = Flow Cytometry, FA = Functional Assays, ICC = Immunocytochemistry, IHC = Immunohistochemistry, IHCF = Immunohistochemistry, Frozen Tissue, IHCP = Immunohistochemistry, Paraffin-embedded Tissue, IF = Immunofluorescence Microscopy, IP = Immunoprecipitation, WB = Western Blot, EM = electron microscopy


*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.