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Recombinant Human BMP-3 (Carrier-free)

Sizes available: 10 µg, 50 µg, 100 µg, 500 µg
Applications: Bioassay
SKU: 21-7172
Recombinant Human BMP-3 (Carrier-free) is available for purchase in increments of 1
Product Name Price Qty
Recombinant Human BMP-3 (Carrier-free) ..... Cat.No. 21-7172-U010 ..... Size 10 µg
$76.00
Recombinant Human BMP-3 (Carrier-free) ..... Cat.No. 21-7172-U050 ..... Size 50 µg
$175.00
Recombinant Human BMP-3 (Carrier-free) ..... Cat.No. 21-7172-U100 ..... Size 100 µg
$280.00
Recombinant Human BMP-3 (Carrier-free) ..... Cat.No. 21-7172-U500 ..... Size 500 µg
$859.00

Description

Details

Bone Morphogenetic Proteins (BMPs) belong to the TGF-beta superfamily of proteins. BMPs elicit their effects by signaling through serine/threonine kinase receptors and play key roles in the development of nearly all organs and tissues. BMP-3, also known as osteogenin, is the most abundant BMP in adult bone and is an apparent inhibitor of pro-osteogenic BMPs. BMP-3 activates the TGF-beta/activin pathway which may antagonize the BMP pathway.

Additional Info

Additional Info

Name Recombinant Human BMP-3 (Carrier-free)
Cat. No. 21-7172
Technical Data Sheet Download TDS
Alternative Names Bone Morphogenic Protein-3, Osteogenin, BMP-3A
Amino Acid Sequence MQWIEPRNCA RRYLKVDFAD IGWSEWIISP KSFDAYYCSG ACQFPMPKSL KPSNHATIQS IVRAVGVVPG IPEPCCVPEK MSSLSILFFD ENKNVVLKVY PNMTVESCAC R
Authenticity Verified by N-terminal and Mass Spectrometry analyses (when applicable).
Bioactivity Inhibition of BMP-2-induced alkaline phosphatase production by ATDC-5 cells is measured.
Endotoxin Level Endotoxin level is <0.1 ng/μg of protein (<1 EU/μg).
Molecular Mass Recombinant Human BMP-3 is 25.2 kDa homodimeric disulfide-linked protein consisting of amino acids 361 to 472 of the precursor protein.
Protein Content Content Verified by UV Spectroscopy and/or SDS-PAGE gel.
Purity (%) 95
Source E. coli
Reactivity Human
Research Areas Angiogenesis & Cardiovascular, Differentiation, Bone and Cartilage, Apoptosis, Proliferation, TGF-beta Superfamily, Stem Cells
Reconstitution See Certificate of Analysis (COA) for lot specific reconstitution information.
Applications Bioassay
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Applications Guide:
FC = Flow Cytometry, FA = Functional Assays, ICC = Immunocytochemistry, IHC = Immunohistochemistry, IHCF = Immunohistochemistry, Frozen Tissue, IHCP = Immunohistochemistry, Paraffin-embedded Tissue, IF = Immunofluorescence Microscopy, IP = Immunoprecipitation, WB = Western Blot, EM = electron microscopy


*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.