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Recombinant Human Angiopoietin-1 (Carrier-free)

Sizes available: 5 µg, 20 µg, 100 µg, 500 µg
Applications: Bioassay
SKU: 21-7167
Recombinant Human Angiopoietin-1 (Carrier-free) is available for purchase in increments of 1
Product Name Price Qty
Recombinant Human Angiopoietin-1 (Carrier-free) ..... Cat.No. 21-7167-U005 ..... Size 5 µg
$76.00
Recombinant Human Angiopoietin-1 (Carrier-free) ..... Cat.No. 21-7167-U020 ..... Size 20 µg
$175.00
Recombinant Human Angiopoietin-1 (Carrier-free) ..... Cat.No. 21-7167-U100 ..... Size 100 µg
$800.00
Recombinant Human Angiopoietin-1 (Carrier-free) ..... Cat.No. 21-7167-U500 ..... Size 500 µg
$2,995.00

Description

Details

Angiopoietin-1 (ANG-1, ANGPT1) is a secreted glycoprotein belonging to the angiopoietin family of growth factors that play a critical role in the regulation of angiogenesis and vascular development. Angiopoietin-1 is a ligand for receptor tyrosine kinase Tie-2, and ligation to Tie-2 on vascular endothelial cells promotes blood vessel development and stabilization of mature blood vessels. The process is regulated by Angiopoietin-2, a natural antagonist for Tie-2, and by Tie-1, an inhibitory co-receptor.

Additional Info

Additional Info

Name Recombinant Human Angiopoietin-1 (Carrier-free)
Cat. No. 21-7167
Technical Data Sheet Download TDS
Alternative Names ANGPT1, ANG-1
Amino Acid Sequence SNQRRSPENS GRRYNRIQHG QCAYTFILPE HDGNCRESTT DQYNTNALQR DAPHVEPDFS SQKLQHLEHV MENYTQWLQK LENYIVENMK SEMAQIQQNA VQNHTATMLE IGTSLLSQTA EQTRKLTDVE TQVLNQTSRL EIQLLENSLS TYKLEKQLLQ QTNEILKIHE KNSLLEHKIL EMEGKHKEEL DTLKEEKENL QGLVTRQTYI IQELEKQLNR ATTNNSVLQK QQ
Authenticity Verified by N-terminal and Mass Spectrometry analyses (when applicable).
Bioactivity A dose-dependent proliferation assay with human umbilical vein endothelial cells (HUVECs) is used to determine activity.
Endotoxin Level Endotoxin level is <0.1 ng/μg of protein (<1 EU/μg).
Molecular Mass Recombinant Human Angiopoietin-1 is a 56.3 kDa glycoprotein with a C-terminal His-tag. It migrates under reducing conditions at approximately 60-70 kDa by SDS-PAGE. Based on sequencing, the N-terminus starts with Ser-20 and Asp-70 of the precursor protein
Protein Content Verified by UV Spectroscopy and/or SDS-PAGE gel.
Purity (%) 95
Source HeLa cells
Reactivity Human
Research Areas Apoptosis, Angiogensis & Cardiovascular, Bone and Cartidage
Reconstitution See Certificate of Analysis (COA) for lot specific reconstitution information.
Application Bioassay
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Application Key:
FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHCF = Immunohistochemistry, Frozen Tissue; IHCP = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy


*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.