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PE-Cyanine5 Anti-Human CD45 (2D1)

Sizes available: 25 tests, 100 tests

Applications: FC
SKU: 55-9459
PE-Cyanine5 Anti-Human CD45 (2D1) is available for purchase in increments of 1
Product Name Price Qty
PE-Cyanine5 Anti-Human CD45 (2D1) ..... Cat.No. 55-9459-T025 ..... Size 25 tests
$89.00
PE-Cyanine5 Anti-Human CD45 (2D1) ..... Cat.No. 55-9459-T100 ..... Size 100 tests
$229.00

Description

Details

The 2D1 antibody reacts with human CD45, one of the most abundant hematopoietic markers and one that is expressed on all leukocytes (the Leukocyte Common Antigen, LCA). CD45 is a protein tyrosine phosphatase existing in several isoforms, each being generated and expressed in cell-specific patterns. With its broad cell distribution, CD45 is critical for many leukocyte functions, regulating signal transduction and cell activation associated with the T cell receptor, B cell receptor, and IL-2 receptor. Other forms of CD45, with restricted cellular expression, include CD45R (B220), CD45RA, CD45RB, and CD45RO.

The 2D1 antibody is widely used as a marker for human CD45 expression on peripheral blood T cells, B cells, monocytes, macrophages, and NK cells.

Additional Info

Additional Info

Name PE-Cyanine5 Anti-Human CD45 (2D1)
Cat. No. 55-9459
Technical Data Sheet Download TDS
Alternative Names Leukocyte Common Antigen, LCA, Ly-5, Hle-1
Gene ID 5788
Clone 2D1
Isotype Mouse IgG1, kappa
Reactivity Human
Cross Reactivity No
Format PE-Cyanine5
Applications Flow Cytometry
Citations*

Bradstock KF, Janossy G, Pizzolo G, Hoffbrand AV, McMichael A, Pilch JR, Milstein C, Beverley P and Bollum FJ. 1980. J. Natl. Cancer Inst. 65(1): 33-42.

Schwinzer R. in Knapp W, Dorken B, et al. eds. 1989. Leucocyte Typing IV: White Cell Differentiation Antigens. Oxford University Press. New York. p. 628-634.

Nieminen JK, Sipponen T, Färkkilä M and Vaarala O. 2014. Clin. Exp. Immunol. 177(1): 190-202. (Flow cytometry)

Piątosa B, Wolska-Kuśnierz B, Pac M, Siewiera K, Gałkowska E and Bernatowska E. 2010. Cytometry Part B. 78B: 372-381. (Flow cytometry)

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Applications Guide:
FC = Flow Cytometry, FA = Functional Assays, ICC = Immunocytochemistry, IHC = Immunohistochemistry, IHCF = Immunohistochemistry, Frozen Tissue, IHCP = Immunohistochemistry, Paraffin-embedded Tissue, IF = Immunofluorescence Microscopy, IP = Immunoprecipitation, WB = Western Blot, EM = electron microscopy


*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.