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Description
Details
The MY31 antibody reacts with human CD56, also known as the neural cell adhesion molecule (NCAM), a glycoprotein which is a member of the immunoglobulin superfamily. The 140 kDa isoform of CD56 is expressed on human NK cells and NK-T cells, with increased expression levels on activated NK lymphocytes. The CD56 antigen is also expressed by neurons and is reported to play a role in nervous system development and neural cell-to-cell adhesion.
Clone MY31 also reacts with a subset of CD14+ monocytes in non-human primates, and is reported to be cross-reactive with Chimpanzee, Cynomolgus and Rhesus.
Additional Info
Additional Info
| Name | FITC Anti-Human CD56 (NCAM) (MY31) |
|---|---|
| Cat. No. | 35-0564 |
| Technical Data Sheet | Download TDS |
| Alternative Names | neural cell adhesion molecule (NCAM), Leu-19 |
| Gene ID | 4684 |
| Clone | MY31 |
| Isotype | Mouse IgG1, kappa |
| Reactivity | Human |
| Cross Reactivity | Chimpanzee, Cynomolgus, Rhesus |
| Format | FITC |
| Applications | Flow Cytometry |
| Citations* | Lanier LL, Testi R, Bindl J and Phillips JH. 1989. J Exp Med. 169: 2233-2238. Schlossman SF, Boumsell L, Gilks W et al., eds. 1995. Leucocyte Typing V: White Cell Differentiation Antigens. Oxford University Press. Carter DL, Shieh TM, Blosser RL, Chadwick KR, Margolick JB, Hidreth JE, Clements JE and Zink MC. 1999. Cytometry. 37(1): 41-50. Chan WK, Suwannasaen D, Throm RE, Li Y, Eldridge PW, Houston J, Gray JT, Pui C-H and Leung W. 2015. Leukemia. 29: 387-395. (Flow cytometry) Woltman AM, Op den Brouw ML, Biesta PJ, Shi CC and Janssen HLA. 2011. PLoS ONE 6(1): e15324. doi: 10.1371/journal.pone.0015324. (Flow cytometry) Bleul CC, Wu L, Hoxie JA, Springer TA and Mackay CR. 1997. Proc Natl Acad Sci USA. 94(5): 1925-1930. (Flow cytometry) Brown K and Barratt-Boyes SM. 2009. J Med Primatol. 38(4): 272-278. (Flow cytometry – Rhesus) |
