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Description
Details
The 61D3 antibody is specific for human CD14, a 53-55 kDa GPI-anchored glycoprotein. CD14 is highly expressed on monocytes and to a lesser extent on interfollicular macrophages, and some dendritic cells. Together with LPS-Binding Protein (LBP), CD14 binds to and mediates the innate immune response to bacterial lipopolysaccharide (LPS).
Additional Info
Additional Info
| Name | APC Anti-Human CD14 (61D3) |
|---|---|
| Cat. No. | 20-0149 |
| Technical Data Sheet | Download TDS |
| Alternative Names | LPS-R, Mo2 |
| Gene ID | 929 |
| Clone | 61D3 |
| Isotype | Mouse IgG1, kappa |
| Reactivity | Human |
| Cross Reactivity | No |
| Format | APC |
| Application | Flow Cytometry |
| Citations* | Hogg N, Horton MA. 1987. In: McMichael AJ, Beverley PCL, Cobbold S, et al., eds. Leucocyte Typing III: White Cell Differentiation Antigens. New York, NY: Oxford University Press; 576-602. Haziot A, Chen S, Ferrero E, Low MG, Silber R, Goyert SM. 1988. J Immunol. 141: 547-552. Wright SD, Ramos RA, Tobias PS, Ulevitch RJ, Mathison JC. 1990. Science. 249: 1431-1433. |