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APC Anti-Human CD279 (PD-1) (J110)

Sizes available: 25 tests, 100 tests

Applications: FC
SKU: 20-2797
APC Anti-Human CD279 (PD-1) (J110) is available for purchase in increments of 1
Product Name Price Qty
APC Anti-Human CD279 (PD-1) (J110) ..... Cat.No. 20-2797-T025 ..... Size 25 tests
$120.00
APC Anti-Human CD279 (PD-1) (J110) ..... Cat.No. 20-2797-T100 ..... Size 100 tests
$255.00

Description

Details

The J110 antibody is specific for human CD279, also known as programmed death-1 (PD-1). PD-1 is a 55 kDa glycoprotein member of the Ig superfamily and is expressed on activated T cells, B cells, and myeloid cells. PD-L1 (B7-H1) and PD-L2 (B7-DC) are ligands for CD279 and belong to the B7 gene family. PD-1 is an immune checkpoint and interaction with its ligands results in inhibition of T cell proliferation and cytokine secretion.

Additional Info

Additional Info

Name APC Anti-Human CD279 (PD-1) (J110)
Cat. No. 20-2797
Technical Data Sheet Download TDS
Alternative Names CD279, PD-1, PD1, SLEB2, hPD-1, hPD-l, hSLE1
Gene ID 5133
Clone J110
Isotype Mouse IgG1
Reactivity Human
Cross Reactivity No
Format APC
Application Flow Cytometry
Citations*

Freeman GJ, Long AJ, Iwai Y, et al. 2000. J Exp Med. 192:1027-1034.

Latchman Y, Wood CR, Chernova T, et al. 2001. Nat Immunol. 2(3):261-268.

Bennett F, Luxenberg D, Ling V, et al. 2003. J Immunol. 170(2):711-718.

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Application Key:
FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHCF = Immunohistochemistry, Frozen Tissue; IHCP = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy


*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.