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In Vivo Ready™ Anti-Mouse Fc epsilon Receptor I alpha (FceR1) (MAR-1)

Sizes available: 25 µg, 100 µg
Applications: FC, FA, IHC, IP
SKU: 40-5898
Product Name Price Qty
In Vivo Ready™ Anti-Mouse Fc epsilon Receptor I alpha (FceR1) (MAR-1) ..... Cat.No. 40-5898-U100 ..... Size 100 µg
$103.00
In Vivo Ready™ Anti-Mouse Fc epsilon Receptor I alpha (FceR1) (MAR-1) ..... Cat.No. 40-5898-U500 ..... Size 500 µg
$177.00

Description

Details

The MAR-1 antibody reacts with the Fc epsilon Receptor I alpha chain (FceRIa), a transmembrane protein member of the Ig superfamily. This chain, together with a beta chain and two gamma chains form a tetrameric complex that supports IgE-mediated signaling and subsequent release of chemical mediators of allergy and immediate hypersensitivity. FceR1a is upregulated in the presence of IgE on those cell types which express it, such as Mast cells and Basophils.

The MAR-1 antibody is widely used both in flow cytometry and for depletion of cells in vitro / in vivo. Please choose the appropriate format for each application.

Additional Info

Additional Info

Name In Vivo Ready™ Anti-Mouse Fc epsilon Receptor I alpha (FceR1) (MAR-1)
Cat. No. 40-5898
Technical Data Sheet Download TDS
Alternative Names high affinity IgE receptor , nale, na/le, leaf, ultra leaf, ultra-leaf, functional grade, ivr
Gene ID 2205
Clone MAR-1
Isotype Armenian Hamster IgG
Reactivity Mouse
Cross Reactivity
Format In Vivo Ready™
Applications Flow Cytometry, Functional Assays, IHC, IP
Citations*

Mukai K, BenBarak MJ, Tachibana M, Nishida K, Karasuyama H, Taniuchi I, and Galli SJ. 2012. Blood. 120: 76-85. (Flow cytometry)

Smith KA, Harcus Y, Garbi N, Hammerling GJ, MacDonald AS, and Maizels RM. 2012. Infect. Immun. 80: 3481-3489. (in vivo depletion)

Larson D, Hubner MP, Torrero MN, Morris CP, Brankin A, Swierczewski BE, Davies SJ, Vonakis BM, and Mitre E. 2012. J. Immunol. 188: 4188-4199. (in vitro activation)

Khodoun M, Krishnamurthy D, Strait R, Kucuk Y, and Finkelman F. 2011. J. Immunol. 186: 151.4. (in vitro depletion)

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Applications Guide:
FC = Flow Cytometry, FA = Functional Assays, ICC = Immunocytochemistry, IHC = Immunohistochemistry, IHCF = Immunohistochemistry, Frozen Tissue, IHCP = Immunohistochemistry, Paraffin-embedded Tissue, IF = Immunofluorescence Microscopy, IP = Immunoprecipitation, WB = Western Blot, EM = electron microscopy


*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.