Toll-Free Customer Service (855) 848-6626 Hours 6AM-5PM PST

FREE Shipping on orders over $500*

Your valued source for Immunology Tools

In Vivo Ready™ Anti-Human CD54 (ICAM-1) (15.2)

Sizes available: 100 µg, 500 µg

Applications: FC, FA, IHCF, WB
SKU: 40-0549
Product Name Price Qty
In Vivo Ready™ Anti-Human CD54 (ICAM-1) (15.2) ..... Cat.No. 40-0549-U100 ..... Size 100 µg
$125.00
In Vivo Ready™ Anti-Human CD54 (ICAM-1) (15.2) ..... Cat.No. 40-0549-U500 ..... Size 500 µg
$283.00

Description

Details

The 15.2 antibody reacts with human CD54, also known as ICAM-1 (Intercellular Adhesion Molecule 1), a 90-110 kDa cell surface glycoprotein that is inducibly expressed on both immune and endothelial cells. As its name implies, ICAM-1 participates in cell-cell adhesion between leukocytes and endothelial cells, facilitating leukocyte recruitment and transmigration at sites of inflammation. The ligands for ICAM-1 are also expressed on leukocyte and endothelial cells, and include Mac-1, fibrinogen, and a member of the integrin protein family, LFA-1 (CD11a).

The 15.2 antibody may be used for analysis of ICAM-1 expression in human cells and tissues, and is reported to be cross-reactive with porcine ICAM-1.

Additional Info

Additional Info

Name In Vivo Ready™ Anti-Human CD54 (ICAM-1) (15.2)
Cat. No. 40-0549
Technical Data Sheet Download TDS
Alternative Names Intercellular adhesion molecule-1, ICAM1
Gene ID 3383
Clone 15.2
Isotype Mouse IgG1
Reactivity Human
Cross Reactivity Pig
Format In Vivo Ready™
Applications Flow Cytometry, Functional Assays, IHCF, Western Blot
Citations*

Sommaggio R, Cohnen A, Watzl C, and Costa C. 2012. J. Immunol. 188: 2075-2083. (in vitro blocking - Pig)

Avril M, Tripathi AK, Brazier AJ, Andisi C, Janes JH, Soma VL, Sullivan DJ, Bull PC, Stins MF, and Smith JD. 2012. Proc. Natl. Acad. Sci. 109: E1782-E1790. (in vitro blocking)

Dryden NH, Sperone A, Martin-Almedina S, Hannah RL, Birdsey GM, Khan ST, Layhadi JA et al. 2012. J. Biol. Chem. 287: 12331-12342. (Western Blot)

Di Lorenzo A, Manes TD, Davalos A, Wright PL, and Sessa WC. 2011. Blood. 117: 2284-2295. (in vitro activation/cross-linking)

Kim S, and Nadel JA. 2009. Am. J. Physiol. Lung Cell. Mol. Physiol. 297: L174-L183. (in vitro blocking, Western Blot)

Goto E, Kohrogi H, Hirata N, Tsumori K, Hirosako S, Hamamoto J, Fujii K, Kawano O, and Ando M. 2000. Am. J. Respir. Cell Mol. Biol. 22: 405-411. (Immunohistochemistry – frozen tissue)

Need Another Format? Inquire Here

Applications Guide:
FC = Flow Cytometry, FA = Functional Assays, ICC = Immunocytochemistry, IHC = Immunohistochemistry, IHCF = Immunohistochemistry, Frozen Tissue, IHCP = Immunohistochemistry, Paraffin-embedded Tissue, IF = Immunofluorescence Microscopy, IP = Immunoprecipitation, WB = Western Blot, EM = electron microscopy


*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.