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In Vivo Ready™ Anti-Mouse Ly-6G (1A8)

Sizes available: 100 µg

Applications: FC, FA, IHCF, IHCP, IP
SKU: 40-1276
In Vivo Ready™ Anti-Mouse Ly-6G (1A8) is available for purchase in increments of 1
Product Name Price Qty
In Vivo Ready™ Anti-Mouse Ly-6G (1A8) ..... Cat.No. 40-1276-U100 ..... Size 100 µg
$91.00

Description

Details

The 1A8 antibody binds to mouse Ly-6G, commonly known as Gr-1, a member of the Ly-6 superfamily of GPI-anchored cell surface proteins with roles in cell signaling and cell adhesion. Gr-1 is differentially expressed during development and maturation of cells in the myeloid lineage and is expression at varying stages and levels on monocytes, macrophages, granulocytes, and peripheral neutrophils.

In the mouse, the 1A8 antibody is typically used in combination with the macrophage labeling antibody M1/70 (Anti-CD11b) for phenotypic analysis of monocytes, macrophages and granulocytes. Note: for identification of Ly-C, an alternative antibody, clone RB6-8C5, has been reported to cross-react with Ly-6C on cells expressing this antigen (Fleming et al. 1993. J. Immunol. 151:2399-2408 and Sasmono et al. 2007. J. Leukoc. Biol. 82: 111-123) and has been cited in the literature for identification of Ly-6G/Ly-6C.

Additional Info

Additional Info

Name In Vivo Ready™ Anti-Mouse Ly-6G (1A8)
Cat. No. 40-1276
Technical Data Sheet Download TDS
Alternative Names Gr-1
Gene ID 546644
Clone 1A8
Isotype Rat IgG2a, kappa
Reactivity Mouse
Cross Reactivity No
Format In Vivo Ready™
Applications Flow Cytometry, Functional Assays, IHCF, IHCP, IP
Citations*

Kamaly N, Fredman G, Subramanian M, Gadde S, Pesic A, Cheung L, Fayad ZA, Langer R, Tabas I, and Cameron O. 2013. Proc. Natl. Acad. Sci. 110. 6506-6511. (flow cytometry).

Stinn W, Buettner A, Weiler H, Friedrichs B, Luetjen S, van Overveld F, Meurrens K, Janssens K, Gebel S, Stabbert R, and Haussman H-J. 2013. Toxicol. Sci. 131: 596-611 (flow cytometry).

Enoksson M, Moller-Westerberg C, Wicher G, Fallon PG, Forsberg-Nilsson K, Lunderius-Andersson C, and Nilsson G. 2013. Blood. 121. 530-536 (flow cytometry).

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Applications Guide:
FC = Flow Cytometry, FA = Functional Assays, ICC = Immunocytochemistry, IHC = Immunohistochemistry, IHCF = Immunohistochemistry, Frozen Tissue, IHCP = Immunohistochemistry, Paraffin-embedded Tissue, IF = Immunofluorescence Microscopy, IP = Immunoprecipitation, WB = Western Blot, EM = electron microscopy


*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.