Toll-Free Customer Service (855) 848-6626 Hours 6AM-3PM PST

FREE Shipping on orders over $500*

Your valued source for Immunology Tools

Biotin Anti-Mouse CD154 (MR1)

Sizes available: 25 µg, 100 µg

Applications: FC
SKU: 30-1541
Biotin Anti-Mouse CD154 (MR1) is available for purchase in increments of 1
Product Name Price Qty
Biotin Anti-Mouse CD154 (MR1) ..... Cat.No. 30-1541-U025 ..... Size 25 µg
$31.00
Biotin Anti-Mouse CD154 (MR1) ..... Cat.No. 30-1541-U100 ..... Size 100 µg
$94.00

Description

Details

The MR1 antibody is specific for mouse CD154, a 39 kD glycoprotein that is primarily expressed on activated T cells. CD154 (CD40 ligand, gp39) binds to CD40 expressed on antigen presenting cells and mediates important costimulatory functions between these cells. Signals generated via cognate interactions between CD154-CD40 on activated T and B cells are required for T-dependent B cell responses. The MR1 antibody is reported to block interaction of CD154 with CD40.

Additional Info

Additional Info

Name Biotin Anti-Mouse CD154 (MR1)
Cat. No. 30-1541
Technical Data Sheet Download TDS
Alternative Names CD40L, TRAP, Ly-62, TNFSF5
Gene ID 21947
Clone MR1
Isotype Armenian Hamster IgG
Reactivity Mouse
Cross Reactivity No
Format Biotin
Applications Flow Cytometry
Citations*

Noelle RJ, Roy M, Shepherd DM, Stamenkovic I, Ledbetter JA, Aruffo A. 1992. Proc Natl Acad Sci U S A. 89(14):6550-6554.

Foy TM, Laman JD, Ledbetter JA, Aruffo A, Claassen E, Noelle RJ. 1994. J Exp Med. 180(1):157-163.

Laman JD, Claassen E, Noelle RJ. 1996. Crit Rev Immunol. 16(1):59-108.

Grewal IS, Flavell RA. 1998. Annu Rev Immunol. 16:111-35.

Need Another Format? Inquire Here

Applications Guide:
FC = Flow Cytometry, FA = Functional Assays, ICC = Immunocytochemistry, IHC = Immunohistochemistry, IHCF = Immunohistochemistry, Frozen Tissue, IHCP = Immunohistochemistry, Paraffin-embedded Tissue, IF = Immunofluorescence Microscopy, IP = Immunoprecipitation, WB = Western Blot, EM = electron microscopy


*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.