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APC Anti-Mouse CD252 (OX40 Ligand) (RM134L)

Sizes available: 25 µg, 100 µg

Applications: FC
SKU: 20-5905
APC Anti-Mouse CD252 (OX40 Ligand) (RM134L) is available for purchase in increments of 1
Product Name Price Qty
APC Anti-Mouse CD252 (OX40 Ligand) (RM134L) ..... Cat.No. 20-5905-U025 ..... Size 25 µg
$51.00
APC Anti-Mouse CD252 (OX40 Ligand) (RM134L) ..... Cat.No. 20-5905-U100 ..... Size 100 µg
$136.00

Description

Details

The RM134L antibody recognizes CD252, also known as OX-40 Ligand or CD134 Ligand, a member of the TNF superfamily that is present on the surface of antigen presenting cells and activated B lymphocytes. The OX-40 Ligand interacts with OX-40 (CD134) which is expressed primarily on activated T cells. This costimulatory interaction leads to increased proliferation and IL-2 production responses of activated T cells, and at the same time enhances proliferation and immunoglobulin secretion by activated B cells.

The RM134L antibody is useful for flow cytometric detection of CD252 on stimulated mouse splenocytes. It has also been reported to block the costimulatory activity of OX-40 Ligand. Please choose the appropriate format for each application.

Additional Info

Additional Info

Name APC Anti-Mouse CD252 (OX40 Ligand) (RM134L)
Cat. No. 20-5905
Technical Data Sheet Download TDS
Alternative Names CD134L, CD134 Ligand, OX-40L, OX-40 Ligand, TNFSF4, Tumor necrosis factor ligand superfamily member 4, gp34
Gene ID 22164
Clone RM134L
Isotype Rat IgG2b, kappa
Reactivity Mouse
Cross Reactivity No
Format APC
Applications Flow Cytometry
Citations*

Akiba H, Oshima H, Takeda K, Atsuta M, Nakano H, Nakajima A, Nohara C, Yagita H and Okumura K. 1999 J Immunol. 162(12): 7058-7066. (Flow cytometry, in vitro blocking)

Stuber E, Neurath M, Calderhead D, Fell HP and Strober W. 1995 Immunity. 2(5): 507-521.

Sibilano R, Frossi B, Suzuki R, D'Incà F, Gri G, Piconese S, Colombo MP, Rivera J and Pucillo CE. 2012 Journal of Allergy Clin Immunol. 130(3): 751–760. (Blocking)

van der Merwe M, Abdelsamed HA, Seth A, Ong T, Vogel P and Pillai AB. 2013 J Immunol. 191(11): 5764-5776 (Flow cytometry)

Need Another Format? Inquire Here

Applications Guide:
FC = Flow Cytometry, FA = Functional Assays, ICC = Immunocytochemistry, IHC = Immunohistochemistry, IHCF = Immunohistochemistry, Frozen Tissue, IHCP = Immunohistochemistry, Paraffin-embedded Tissue, IF = Immunofluorescence Microscopy, IP = Immunoprecipitation, WB = Western Blot, EM = electron microscopy


*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.